“Chronic pain is one of the frequently encountered clinical problems that is difficult to cure. Hyperbaric oxygen (HBO) therapy has been reported in chronic pain syndromes with promising results. In this review, we focus on the effectiveness of HBO in fibromyalgia syndrome, complex regional pain syndrome, myofascial pain syndrome, migraine, and cluster headaches. HBO may be beneficial if appropriate patients are selected. HBO is a reliable method of treatment

Hyperbaric oxygen is a promising treatment modality in chronic pain management. Physicians dealing with chronic pain syndromes must consider HBO when conventional treatments fail.”

---

“Twenty-five studies examining the role of HBOT in animal models of pain and human clinical trials were found and reviewed for this narrative review.

 Hyperbaric Oxygen Therapy has been shown to reduce pain using animal models. Early clinical research indicates HBOT may also be useful in modulating human pain; however, further studies are required to determine whether HBOT is a safe and efficacious treatment modality for chronic pain conditions.”